<div dir="ltr"><font face="arial, helvetica, sans-serif">Dear COD administrator, </font><div><font face="arial, helvetica, sans-serif"><br></font></div><div><font face="arial, helvetica, sans-serif">I'm Hiromu Egashira, computer chemist, belong to ONO Pharmaceutical in Japan. COD is quite useful for me to search ligand crystal data.</font></div><div><font face="arial, helvetica, sans-serif">I would like to search many compounds at once, so I would like to download the SMILES from COD. I found the page "Obtaining COD", but I couldn't find how to download SMILES. I think you have SMILES file, because you write "<span style="color:rgb(255,0,0);text-align:center">substructure search by SMILES is currently available in a subset of COD containing </span><span style="color:rgb(255,0,0);text-align:center;white-space:nowrap">160697 </span><span style="color:rgb(255,0,0);text-align:center">structures."</span></font></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif">I will appreciate if you could answer my question.</font></font></span></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif"><br></font></font></span></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif">regards,</font></font></span></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif"><br></font></font></span></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif">Hiromu</font></font></span></div><div><span style="text-align:center"><font color="#000000" style=""><font face="arial, helvetica, sans-serif">

<div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px">------------------------------<wbr>------------------------------<wbr>------------------------------<wbr>----------<u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px"><span class="gmail-il">Hiromu</span><span> </span><span class="gmail-il">Egashira</span><u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px"><span class="gmail-il">Group</span><span> </span><span class="gmail-il">Head</span>,<span> </span><span class="gmail-il">Group</span><span> </span>II, Medicinal Chemistry Laboratories III<u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px">ONO Pharmaceutical Co., Ltd.<u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px"><a href="https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmaps.google.com%2F%3Fq%3D3-1-1%2BSakurai%2C%2BShimamoto-cho%2C%2BMishima-gun%2C%2BOsaka%26entry%3Dgmail%26source%3Dg&data=02%7C01%7CKaren.Williams%40crl.com%7C08cdf87ea09a441d1afd08d58a5e1631%7C374f8930e1504031bb35483215fe5900%7C0%7C0%7C636567059072351027&sdata=nMmYFhEeBKNiM6R8oXrG4ADH%2BFoiaRRtVlNeC6NZH6k%3D&reserved=0" target="_blank" style="color:rgb(17,85,204)">3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka</a><span> </span>618-8585, Japan<u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px">Phone<span> </span><a href="tel:+81%2075-961-1151" target="_blank" style="color:rgb(17,85,204)">+81-75-961-1151</a>, Fax<span> </span><a href="tel:+81%2075-962-9314" target="_blank" style="color:rgb(17,85,204)">+81-75-962-9314</a><u></u><u></u></p></div><div style="color:rgb(34,34,34);font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:0px;background-color:rgb(255,255,255);text-decoration-style:initial;text-decoration-color:initial"><p class="MsoNormal" style="margin:0px">------------------------------<wbr>------------------------------<wbr>------------------------------<wbr>----------</p></div>

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